ncRNA name | hsa-miR-140 |
ncRNA Category | miRNA |
Disease name | uveal melanoma (UM) |
Species | Homo sapiens |
Tissues/Cell_line | UM samples and paired normal tissues; UM cell lines MUM-2C, OCM-1A, MUM-2B and C918; melanocyte cell line D78 |
Methods | qPCR, Western blot, MTT assay, colony information asssay, transwell assay |
Expression pattern | down-regulated |
Functional description | miR-140 was downregulated in the uveal melanoma tissues compared to normal tissues and cell lines. The expression level of MALAT1 was inversely correlated with the expression level of miR-140 in uveal melanoma tissues. |
PubMed ID | 27725873 |
Year | 2016 |
Title | Long noncoding RNA MALAT1 promotes uveal melanoma cell growth and invasion by silencing of miR-140. |
Drug-related ncRNA | NO |
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